thalidomide (Rx)

Dosage Forms & Strengths

capsule

• 50mg

• 100mg

• 150mg

• 200mg

Erythema Nodosum Leprosum (ENL)

Indicated for acute treatment of cutaneous manifestations of moderate-to-severe erythema nodosum leprosum (ENL); also indicated as maintenance therapy for prevention and suppression of cutaneous recurrence

Also indicated as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence

Note: Not indicated as monotherapy for ENL in the presence of moderate-to-severe neuritis

Initial: 100-300 mg PO qDay with water, preferably at bedtime at least 1 hr after evening meal

Weight <50 kg: Initiate at low end of dose range

Severe cutaneous ENL or patient previously requiring higher doses: May start at 400 mg/day (qHS or in divided doses at least 1 hr pc)

Consider concomitant use of corticosteroids in patients with moderate-to-severe neuritis associated with a severe ENL reaction; taper steroid and discontinued when neuritis has ameliorated

https://reference.medscape.com/drug/thalomid-thalidomide-343211

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