epirubicin (Rx)

Dosage Forms & Strengths

injectable solution

• 2mg/mL as single dose vial containing 50mg/25mL or 200mg/100mL

Adjuvant Breast Cancer Treatment

Indicated as a component of adjuvant therapy in patient with evidence of axillary node tumor involvement following resection of primary breast cancer

Option 1 (Day 1 dose schedule)

• Day 1: Epirubicin 100 mg/m² IV, AND 5-fluorouracil 500 mg/m² IV, AND cyclophosphamide 500 mg/m² IV  

• Repeat q21Days x 6 cycles

Option 2 (Divided dose schedule)

• Days 1 and 8: Epirubicin 60 mg/m² IV, AND 5-fluorouracil 500 mg/m² IV, AND

• Days 1-14: Cyclophosphamide 75 mg/m² PO

• Repeat q28Days x 6 cycles

https://reference.medscape.com/drug/epirubicin-342251

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