valrubicin (Rx)

Dosage Forms & Strengths

intravesical solution

• 40mg/mL

Bladder Carcinoma

Indicated for intravesicular treatment of BCG-Refractory bladder carcinoma in situ

800 mg intravesical once weekly for 6 weeks; retain in bladder for 2 hours before voiding

Monitor q3month for recurrence/progression of CIS

Administration

Reconstitution: withdraw contents of 4 vials, each containing 200 mg in 5 mL (allowed to warm to room temp without heating), & dilute with 55 mL NS

Instill slowly via gravity flow through a urinary catheter (following sterile insertion)

Withdraw the catheter & allow patient to retain solution for 2 hours

After 2 hours, patient should void

Use caution when preparing, handling, and disposal

https://reference.medscape.com/drug/valrubicin-342236

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