temozolomide (Rx)

Dosage Forms & Strengths

capsule

• 5mg

• 20mg

• 100mg

• 140mg

• 180mg

• 250mg

powder for injection

• 100mg/vial

Anaplastic Astrocytoma

Newly diagnosed

• Indicated for adjuvant treatment of adults with newly diagnosed anaplastic astrocytoma

• Begins 4 weeks after end of radiotherapy

• Administer orally in a single dose on days 1-5 of a 28-day cycle for 12 cycles

• Cycle 1

• Days 1-5: 150 mg/m2 PO qDay  

• Cycles 2-12

• Days 1-5: 200 mg/m2 PO qDay if patient experienced no or minimal toxicity in Cycle 1

• Note: if dose was not escalated at start of Cycle 2, do not increase dose during Cycles 3-6

https://reference.medscape.com/drug/temodar-temozolomide-342229

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