brigatinib (Rx)

Dosage Forms & Strengths

tablet

• 30mg

• 90mg

• 180mg

Non-Small Cell Lung Cancer

Indicated for anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC)

90 mg PO qDay for the first 7 days; if 90 mg/day tolerated, increase to 180 mg PO qDay

Continue until disease progression or unacceptable toxicity

Dosage Modifications

If treatment is interrupted for ≥14 days for reasons other than adverse reactions, resume at 90 mg qDay for 7 days before increasing to previously tolerated dose

Dose reductions

Once discontinued, do not subsequently increase dose

Permanently discontinue if unable to tolerate 60 mg/day

https://reference.medscape.com/drug/alunbrig-brigatinib-1000123

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