trabectedin (Rx)

Dosage Forms & Strengths

lyophilized powder for reconstitution

• 1mg/vial

injection solution

• 1mg/20mL/vial (0.05 mg/mL)

Soft Tissue Sarcoma

Indicated for unresectable or metastatic liposarcoma or leiomyosarcoma in patients who have received a prior anthracycline-containing regimen

Premedicate with dexamethasone prior to each dose

1.5 mg/m² IV q3wk until disease progression or unacceptable toxicity

Infuse over 24 hr via a central venous line

Note: Patients must have normal bilirubin and AST or ALT ≤2.5 x ULN; there is no recommended dose in patients with serum bilirubin levels above the institutional ULN

https://reference.medscape.com/drug/yondelis-trabectedin-999997

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