altretamine
Dosing & Uses
Dosage Forms & Strengths
capsule
50mg
Recurrent Ovarian Cancer
Indicated for recurrence following alkylating agent or cisplatin treatment
260 mg/m²/day PO divided q6hr for 14-21 days of a 28-day cycle
Dosage Modifications
Renal or hepatic impairment: Dose adjustment not required
Temporarily hold and restart at 200 mg/m²/day if any of the following develop
GI intolerance unresponsive to symptomatic treatment
WBC <2000/mm³ or granulocytes <1000/mm³
Platelets <75,000/mm³
Progressive neurotoxicity
……see more….
https://reference.medscape.com/drug/hexalen-altretamine-342191
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